Saltatory Conduction in Myelinated Fibres Lead To Faster Impulses
Saltatory Conduction
The process by which an action potential jumps from one node of Ranvier to the next, rather than traveling continuously along the axon.
- In myelinated nerve fibres, the process of saltatory conduction allows action potentials to propagate at much higher speeds compared to unmyelinated fibres.
- This is due to the presence of nodes of Ranvier, small gaps between the myelin sheaths where ion channels and pumps are concentrated.

- Imagine you’re in a relay race. Instead of running the entire distance, you could leap from one checkpoint to the next, skipping large sections of the track.
- This is how saltatory conduction works in neurons, allowing nerve impulses to travel at incredible speeds.
- The rapid transmission of nerve impulses in myelinated axons, where the impulse "jumps" between nodes of Ranvier, bypassing the insulated sections of the axon.
Myelin Is The Insulating Layer
- Myelin is a fatty substance that wraps around axons in layers, forming the myelin sheath.
- This sheath acts like insulation on a wire, preventing electrical leakage and ensuring efficient signal transmission.
- Myelin is produced by specialized cells:
- Schwann cells in the peripheral nervous system.
- Oligodendrocytes in the central nervous system.

- Think of myelin as the rubber coating on electrical wires.
- It prevents short circuits and keeps the current flowing smoothly.
Nodes of Ranvier Are The Key to Saltatory Conduction
Nodes of Ranvier
Gaps in the myelin sheath where the axonal membrane is exposed.
- Myelin doesn’t cover the entire axon.
- There are small gaps called nodes of Ranvier, spaced about 1–2 mm apart.
- The nodes of Ranvier are small gaps between these myelin segments where the axon membrane is exposed to the extracellular fluid.
- These nodes contain a high concentration of voltage-gated sodium and potassium channels, essential for the generation and propagation of action potentials.
Ion channels and pumps are concentrated at the nodes of Ranvier, enabling action potentials to regenerate at each node.


